Radioprotective Potential of Phycocyanin (PC) from Spirulina platensis Against Radiation Induced Haematological Changes in Wistar Rat.

Spirulina platensis, a blue green microalga, is proved for its antioxidant potential. Phycocyanin the phytopigment from Spirulina plays important role in cell protection from oxidative damage by scavenging reactive oxygen species (ROS) The therapeutic potential of Spirulina placed it as a key component in modern herbal drug development and dietary supplement. This study investigates the radioprotective potential of Phycocyanin, a phytopigment from Spirulina platensis, against gamma radiation exposure in Wistar rats. The Whole-body gamma radiation exposure at a dose 8 Gy was carried out. Analysis of post irradiated behavioural and haematological parameters shows less severe alterations and substantial recovery in phycocyanin pretreated group at a safe dose of phycocyanin 400 mg/ kg body weight within two weeks.