Pharmacognostical Studies and Evaluation of Anti-inflammatory and Antinociceptive Activity of Artocarpus lakoocha Fruit Extracts

Artocarpus lakoocha Roxb., belonging to family Moraceae is a valuable tropical tree species native to India. A detailed pharmacognostic study on the fruits of Artocarpus lakoochawas carried out. This study includes preparation of different extracts by successive solvent extraction. Fluorescence analysis of different extracts was noted under UV light and ordinary light. Different physicochemical parameters such as, extractive value, loss on drying, ash value was carried out. Preliminary phytochemical evaluation for different extract shows the presence of glycosides, carbohydrates, steroids, saponins, Fixed oils & Fats and phenolic compound. Extracts of Artocarpus lakoocha were tested for anti-inflammatory and analgesic activities. The analgesic activity was carried out using hot plate, tail flick and tail immersion methods with the help of petroleum ether, chloroform and ethanolic extracts. The anti-inflammatory activities were carried out using carrageenan-induced hind paw edema model of same extracts. In all the methods studied, the chloroform extract at dose of 400mg/kg, body weight, p.o. was found to be most active among all the test extracts.