Association Between Peritoneal Carcinomatosis and Histopathologic Type of Cancer

Objective: To evaluate histopathological subtypes and to assess age and gender wise differences in histopathological subtypes among patients with peritoneal carcinomatosis presenting at tertiary care hospital of Karachi, Pakistan. Study Design: Cross-sectional study. Place and Duration of Study: Medical Oncology Department, Jinnah Postgraduate Medical Center, Karachi Pakistan, from Apr 2019 to Apr 2020. Methodology: One forty patients of age less than 70 years of any gender with peritoneal carcinomatosis were enrolled. The data regarding socio-demographic factors was collected on pre-designed questionnaire. Patients were undergone for CT scan and results were used to identify cancer type, stage and histological subtype of tumor. Results: Of 140 patients, the mean age was 44.94±11.62 years. About 78 patients had ovarian cancer (55.7%), 27 had colorectal cancer (19.3%) and 35 patients had gastric cancer (25%) respectively. Most of the patients had serous histology 36(26%) followed by adenocarcinoma 33(24%). There was statistically significant difference in histological subtypes with respect to gender (p=0.001). Conclusion: Serous histology is the most common histology among patients with peritoneal carcinomatosis and gender-wise the proportions of histological sub-types varies significantly.