Patient Characteristics and Treatment Outcomes of Nasopharyngeal Carcinoma in Nonendemic Regions
This cohort study contributes to the evolving body of knowledge on NPC in nonendemic regions, finding a shift toward WHO type III tumors and underscoring the association of EBV status with survival outcomes, while highlighting the lack of association between human papillomavirus status and outcomes. Smoking history, advanced stage at diagnosis, male sex, and increasing age emerged as adverse factors. Notably, WHO type I tumors demonstrated particularly poor outcomes, highlighting the need for more intensive follow-up in this subgroup.
Authors
- Marcelo Raul Bonomi (ORCID: https://orcid.org/0000-0002-9399-3608)
- James William Rocco (ORCID: https://orcid.org/0000-0001-5312-0303)
- Menglin Xu
- J.C. Grecula (ORCID: https://orcid.org/0009-0007-1817-063X)
- David Joseph Konieczkowski (ORCID: https://orcid.org/0000-0002-3448-0917)
- Ricardo L. Carrau
- Matthew Old (ORCID: https://orcid.org/0000-0003-1795-5877)
- Ahmed ElGuindy (ORCID: https://orcid.org/0000-0002-3598-8413)
- Kyle K. VanKoevering (ORCID: https://orcid.org/0000-0001-5921-7042)
- Mohammad Bilal Alsavaf (ORCID: https://orcid.org/0000-0002-6722-2244)
- Sujith Baliga (ORCID: https://orcid.org/0000-0002-8032-2071)
- Matthew Marquardt (ORCID: https://orcid.org/0000-0001-8334-2222)
- Dukagjin M. Blakaj (ORCID: https://orcid.org/0000-0002-1718-9642)
- Emile Gogineni (ORCID: https://orcid.org/0000-0001-6222-311X)
- Priyanka Bhateja (ORCID: https://orcid.org/0000-0001-9515-0498)
- Moataz D. Abouammo (ORCID: https://orcid.org/0000-0001-6970-1874)
Institutions
- The Ohio State University Wexner Medical Center (US)
- The Ohio State University (US)
Publication Details
- Journal
- JAMA Network Open
- Published
- 2025-03-26
- DOI
- https://doi.org/10.1001/jamanetworkopen.2025.1895
- Citations
- 13
- Primary Topic
- Head and Neck Cancer Studies
- Type
- article
- Field-Weighted Citation Impact
- 24.02