Decreased Lactococcus lactis and Propionic Acid in Feces of Patients with Moyamoya Disease: Possible Implications of Immune Dysregulation
Decreased L. lactis can result in reduced lactic acid and propionic acid levels in the feces of the patients. This imbalance in the gut microbiome and SCFA/organic acid levels could contribute to immune dysregulation underlying the vascular remodeling seen in MMD. .
Authors
- Daisuke Ando (ORCID: https://orcid.org/0009-0000-8180-7196)
- Ryosuke Tashiro (ORCID: https://orcid.org/0000-0002-1099-303X)
- Arata Nagai
- Keita Tominaga (ORCID: https://orcid.org/0009-0000-3897-0414)
- Takaaki Abe (ORCID: https://orcid.org/0000-0003-3170-4660)
- Hidetaka Tokuno (ORCID: https://orcid.org/0000-0002-3973-092X)
- Hidenori Endo (ORCID: https://orcid.org/0000-0003-1472-6032)
- Takeya Sato (ORCID: https://orcid.org/0000-0003-2409-1819)
- Kuniyasu Niizuma (ORCID: https://orcid.org/0000-0001-9282-6499)
- Atsushi Kanoke (ORCID: https://orcid.org/0000-0002-9202-6069)
- Hiroyuki Sakata (ORCID: https://orcid.org/0000-0003-0745-9538)
- Teiji Tominaga (ORCID: https://orcid.org/0000-0003-3411-2900)
- Takashi Aikawa (ORCID: https://orcid.org/0000-0002-0510-5624)
- Mayuko Otomo
Institutions
- Tohoku University (JP)
- Tohoku University Hospital (JP)
- Kohnan Hospital (JP)
Publication Details
- Journal
- Cerebrovascular Diseases
- Published
- 2025-03-26
- DOI
- https://doi.org/10.1159/000545478
- Citations
- 1
- Primary Topic
- Moyamoya disease diagnosis and treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.67