Common Haplotypes within the Chromosome 1q31.3 Region Determine Systemic Concentrations of the Entire Complement Factor H Protein Family
The established reference intervals and identified genetic effects provide a benchmark for further research and emphasize the importance of including all family members when studying their role in both health and disease.
Authors
- Richard B. Pouw (ORCID: https://orcid.org/0000-0003-3469-8454)
- Jin Liu (ORCID: https://orcid.org/0000-0002-4050-7207)
- Taco W. Kuijpers (ORCID: https://orcid.org/0000-0002-7421-3370)
- Karin van Leeuwen (ORCID: https://orcid.org/0000-0001-7783-655X)
- Erik J. M. Toonen (ORCID: https://orcid.org/0000-0001-9039-635X)
- Gerard van Mierlo
- Robert A. Anstadt
- Mara van Rossum
- Burt T. Richards (ORCID: https://orcid.org/0000-0003-1789-2335)
- Gregory S. Hageman (ORCID: https://orcid.org/0000-0001-6360-829X)
- Judy Geissler (ORCID: https://orcid.org/0000-0002-2645-1008)
- Bert R.J. Veuskens
- Mieke C. Brouwer
- Emi Cattenstart
Institutions
- Sanquin (NL)
- Emma Kinderziekenhuis (NL)
- Hycult Biotech (Netherlands) (NL)
- Amsterdam University Medical Centers (NL)
- University of Amsterdam (NL)
Publication Details
- Journal
- Journal of Innate Immunity
- Published
- 2025-03-26
- DOI
- https://doi.org/10.1159/000545342
- Citations
- 1
- Primary Topic
- Complement system in diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.80
Funders
- European Commission