Mitochondria‐Rich Extracellular Vesicles From Bone Marrow Stem Cells Mitigate Muscle Degeneration in Rotator Cuff Tears in a Rat Model Through Macrophage M2 Phenotype Conversion
Mitochondrial transfer via BMSC-EVs may offer a therapeutic strategy to prevent muscle degeneration in patients with rotator cuff tear.
Authors
- Wan Hu (ORCID: https://orcid.org/0000-0003-3728-1275)
- Jian Xu (ORCID: https://orcid.org/0000-0002-8162-889X)
- Jingzeng Wang (ORCID: https://orcid.org/0000-0002-3458-0635)
- Xing Gao (ORCID: https://orcid.org/0000-0001-8893-2416)
- Yuanyuan Chen (ORCID: https://orcid.org/0000-0001-5435-3248)
- Li Xiao (ORCID: https://orcid.org/0000-0002-3053-4930)
- Yulong Shi (ORCID: https://orcid.org/0000-0002-1924-8650)
Institutions
- Wuhan University (CN)
- Zhongnan Hospital of Wuhan University (CN)
- Central Hospital of Wuhan (CN)
- Wuhan General Hospital of Guangzhou (CN)
- Tongji Hospital (CN)
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- Arthroscopy The Journal of Arthroscopic and Related Surgery
- Published
- 2025-03-25
- DOI
- https://doi.org/10.1016/j.arthro.2025.03.033
- Citations
- 2
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 1.61
Funders
- Wuhan University
- Zhongnan Hospital of Wuhan University
- Fundamental Research Funds for the Central Universities