Impact of the COVID-19 pandemic on the epidemiology and clinical course of tuberculosis: expected and paradoxical consequences
Our results are consistent with the reportedly higher ability of Beijing B0/W148 strains (compared to Beijing 94-32) to acquire resistance to anti-TB drugs, their increased virulence and transmissibility. Thus, the seemingly paradoxical, milder clinical course of TB in patients who further developed COVID-19 is explained by a shift in the ratio of M. tuberculosis subtypes due to syndemic interaction between the two epidemics.
Authors
- Igor Mokrousov (ORCID: https://orcid.org/0000-0001-5924-0576)
- Ya. Sh. Schwartz (ORCID: https://orcid.org/0000-0002-3036-9795)
- Anna Vyazovaya (ORCID: https://orcid.org/0000-0001-9140-8957)
- Н. В. Турсунова (ORCID: https://orcid.org/0009-0003-7796-6292)
Institutions
- Novosibirsk Tuberculosis Research Institute (RU)
- Saint Petersburg Pasteur Institute (RU)
Publication Details
- Journal
- BMC Infectious Diseases
- Published
- 2025-03-26
- DOI
- https://doi.org/10.1186/s12879-025-10793-x
- Citations
- 3
- Primary Topic
- Tuberculosis Research and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 4.19
Funders
- Russian Foundation for Basic Research