EFFECT OF MICROAMPERE CURRENT ON CLINICAL STRAINS OF ACINETOBACTER BAUMANNII WITH MULTIPLE DRUG RESISTANCE AND THE MANIFESTATION OF THE BIOELECTRIC EFFECT
versity, Vinnytsya and is a fragment of the research work "Research of the biological properties of pathogens of healthcare-associated infections and the development of means of combating them" (state registration number 0123U101070).Introduction.Resistance of gram-negative bacteria to last-line drugs has become a serious global problem, the scale of which continues to gain momentum.Non-fermenting gram-negative bacteria, in particular Acinetobacter baumannii, Pseudomonas aeruginosa Stenotrophomonas maltophilia, which show high resistance and limit therapeutic options, and the use of alternative drugs, in particular tigecycline or colistin, is often accompanied by problems related to their efficacy and potential toxicity attract the special attention of researchers and cliniciansA. baumannii is one of the six main dangerous nosocomial pathogens in the ESKAPE short list (Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, Enterobacter spp.) of the World Health Organization (WHO) with high rates of morbidity and mortality [4][5][6].In the updated (May 17, 2024) list of WHO priority pathogens A. baumannii, resistant to carbapenems (Carbapenem-resistant A. baumannii -CRAB)
Authors
- Олександр Назарчук (ORCID: https://orcid.org/0000-0001-7581-0938)
- Т. V. Denysko (ORCID: https://orcid.org/0000-0002-2188-2001)
- Halyna Nazarchuk (ORCID: https://orcid.org/0000-0003-3902-1741)
- V. V. Bebyk (ORCID: https://orcid.org/0000-0001-7110-8543)
- О.М. Пархоменко
Institutions
- Odessa National Medical University (UA)
- National Pirogov Memorial Medical University, Vinnytsya (UA)
Publication Details
- Journal
- Bulletin of Problems Biology and Medicine
- Published
- 2025-01-01
- DOI
- https://doi.org/10.29254/2077-4214-2025-1-176-382-389
- Primary Topic
- Microbial Inactivation Methods
- Type
- article
- Field-Weighted Citation Impact
- 0.00