Derivation and validation of a model to predict treatment failure among under five children with severe community acquired pneumonia who are admitted at Debre Tabor specialized comprehensive hospital
The incidence of treatment failure among children with severe community-acquired pneumonia was high in Debre Tabor comprehensive hospital. The previous history of severe community-acquired pneumonia, abnormal pulse rate, chest indrowing, anemia, HIV status, and plural effusion were the significant factors to develop the predictive model. The model had good discriminatory performance and internally valid. Similarly, the model has a good calibration ability with an insignificant loss of accuracy from the original. The models can have the potential to improve treatment outcomes in the clinical settings. But needs external validation before use.
Authors
- Amare Kassaw (ORCID: https://orcid.org/0000-0003-1321-9151)
- Muluken Chanie Agimas (ORCID: https://orcid.org/0000-0003-0808-124X)
- Tigabu Kidie Tesfie (ORCID: https://orcid.org/0000-0002-8250-125X)
- Nebiyu Mekonnen Derseh (ORCID: https://orcid.org/0000-0003-1355-2763)
Institutions
- Debre Tabor University (ET)
- University of Gondar (ET)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-03-26
- DOI
- https://doi.org/10.1371/journal.pone.0320448
- Citations
- 1
- Primary Topic
- Pneumonia and Respiratory Infections
- Type
- article
- Field-Weighted Citation Impact
- 1.35