Derivation and validation of a model to predict treatment failure among under five children with severe community acquired pneumonia who are admitted at Debre Tabor specialized comprehensive hospital

The incidence of treatment failure among children with severe community-acquired pneumonia was high in Debre Tabor comprehensive hospital. The previous history of severe community-acquired pneumonia, abnormal pulse rate, chest indrowing, anemia, HIV status, and plural effusion were the significant factors to develop the predictive model. The model had good discriminatory performance and internally valid. Similarly, the model has a good calibration ability with an insignificant loss of accuracy from the original. The models can have the potential to improve treatment outcomes in the clinical settings. But needs external validation before use.

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Publication Details

Journal
PLoS ONE
Published
2025-03-26
DOI
https://doi.org/10.1371/journal.pone.0320448
Citations
1
Primary Topic
Pneumonia and Respiratory Infections
Type
article
Field-Weighted Citation Impact
1.35
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article

Derivation and validation of a model to predict treatment failure among under five children with severe community acquired pneumonia who are admitted at Debre Tabor specialized comprehensive hospital

Amare Kassaw, Muluken Chanie Agimas, Tigabu Kidie Tesfie, Nebiyu Mekonnen Derseh
1 citations
PLoS ONE
Pneumonia and Respiratory Infections
1.35
article

Derivation and validation of a model to predict treatment failure among under five children with severe community acquired pneumonia who are admitted at Debre Tabor specialized comprehensive hospital

Amare Kassaw, Muluken Chanie Agimas, Tigabu Kidie Tesfie, Nebiyu Mekonnen Derseh
article en
1 citations

Abstract

The incidence of treatment failure among children with severe community-acquired pneumonia was high in Debre Tabor comprehensive hospital. The previous history of severe community-acquired pneumonia, abnormal pulse rate, chest indrowing, anemia, HIV status, and plural effusion were the significant factors to develop the predictive model. The model had good discriminatory performance and internally valid. Similarly, the model has a good calibration ability with an insignificant loss of accuracy from the original. The models can have the potential to improve treatment outcomes in the clinical settings. But needs external validation before use.

PLoS ONEVol. 20(3)
Debre Tabor University (ET), University of Gondar (ET)
Good health and well-being
Openalex Percentile: Top 22%
Pneumonia and Respiratory Infections
1.35
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Derivation and validation of a model to predict treatment failure among under five children with severe community acquired pneumonia who are admitted at Debre Tabor specialized comprehensive hospital — Amare Kassaw, Muluken Chanie Agimas, et al. · PLoS ONE (2025) | TGRS Research Map | TGRS