Comparison of serum levels of cardiac biomarkers during hysterectomies

Aim: The aim of this study was to retrospectively examine the changes in serum cardiac marker enzyme levels in patients who underwent total hysterectomy with laparoscopic and abdominal methods.Material and Methods: This retrospective study included a total of 101 patients randomized between October 2017 and February 2018 in the department of gynecology and obstetrics of a tertiary health center.Total laparoscopic hysterectomy (TLH) was performed in 48 patients (47.5%) and total abdominal hysterectomy (TAH) in 53 patients (52.5%).Demographic data were compared with cardiac marker enzymes (creatine kinase, creatine kinase MB, lactate dehydrogenase, and troponin T levels in the TLH and TAH groups evaluated preoperatively and postoperative 6th and 12th hours.Results: In the TLH group, troponin T level at the 12th hour was significantly higher than those measured at the other two time periods (p <0.001).Troponin T levels at 6th and 12th hours postoperatively in the TAH group were significantly higher than the baseline value (p <0.001).There was a statistically significant difference in the CK-MB level between the three-time points of the TLH group (p = 0.005).Baseline and 12th-hour values were significantly higher than the value measured at the 6th hour.Creatine kinase levels in the TAH and TLH groups were significantly higher at the 12th hour, 6th hour and at baseline (p <0.001).The median creatine kinase level in the TAH group was higher than in the TLH group (p<0.001).Discussion: Cardiac problems that may occur before, during, or after gynecological interventions in female patients may have an unusual clinical presentation.Considering the cardiac risk profile of the patient, in addition to the experience and technical possibilities of the surgeon, is important to prevent complications when the decision is made regarding the realization of hysterectomy using laparoscopic or abdominal methods.