Hydroxyl-modified fullerene C<sub>70</sub>(OH)<sub>8</sub> induces pyroptosis for cancer therapy
This study reports a novel hydroxyl-modified fullerene compound which can induce both apoptosis and pyroptosis in HeLa cells under light irradiation. Additionally, C 70 (OH) 8 @NP demonstrates significant anti-tumor activity in vivo .
Authors
- Liangbing Gan (ORCID: https://orcid.org/0000-0001-6646-3452)
- Zhen Liu (ORCID: https://orcid.org/0000-0001-6816-8342)
- Hang Zhang (ORCID: https://orcid.org/0000-0002-5479-3435)
- Jun‐Long Zhang (ORCID: https://orcid.org/0000-0002-5731-7354)
- Xiaofei Zhu (ORCID: https://orcid.org/0000-0001-5769-9308)
Institutions
- Sinopec (China) (CN)
- Peking University (CN)
- Guizhou Minzu University (CN)
- Beijing National Laboratory for Molecular Sciences (CN)
- Beijing Chemical Industry Research Institute (China) (CN)
- Changchun University of Technology (CN)
Publication Details
- Journal
- Inorganic Chemistry Frontiers
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5qi00548e
- Primary Topic
- Fullerene Chemistry and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00