HealthQ: Unveiling questioning capabilities of LLM chains in healthcare conversations

Effective patient care in digital healthcare requires large language models (LLMs) that not only answer questions but also actively gather critical information through well-crafted inquiries. This paper introduces HealthQ, a novel framework for evaluating the questioning capabilities of LLM healthcare chains. By implementing advanced LLM chains, including Retrieval-Augmented Generation (RAG), Chain of Thought (CoT), and reflective chains, HealthQ assesses how effectively these chains elicit comprehensive and relevant patient information. To achieve this, we integrate an LLM judge to evaluate generated questions across metrics such as specificity, relevance, and usefulness, while aligning these evaluations with traditional Natural Language Processing (NLP) metrics like ROUGE and Named Entity Recognition (NER)-based set comparisons. We validate HealthQ using two custom datasets constructed from public medical datasets, ChatDoctor and MTS-Dialog, and demonstrate its robustness across multiple LLM judge models, including GPT-3.5, GPT-4, and Claude. Our contributions are threefold: we present the first systematic framework for assessing questioning capabilities in healthcare conversations, establish a model-agnostic evaluation methodology, and provide empirical evidence linking high-quality questions to improved patient information elicitation. • We introduce HealthQ, the first to evaluate LLM questioning in healthcare chains. • HealthQ integrates RAG, CoT, and reflection to improve patient question quality. • Validated on two medical datasets with gains in specificity and relevance.

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Publication Details

Journal
Smart Health
Published
2025-03-27
DOI
https://doi.org/10.1016/j.smhl.2025.100570
Citations
12
Primary Topic
Big Data and Business Intelligence
Type
article
Field-Weighted Citation Impact
27.41
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article

HealthQ: Unveiling questioning capabilities of LLM chains in healthcare conversations

Amir M. Rahmani, Ziyu Wang, Hao Li, Di Huang et al.
12 citations
Smart Health
Big Data and Business Intelligence
27.41
article

HealthQ: Unveiling questioning capabilities of LLM chains in healthcare conversations

Amir M. Rahmani, Ziyu Wang, Hao Li, Di Huang, Hye‐Sung Kim, Chae-Won Shin
article en
12 citations

Abstract

Effective patient care in digital healthcare requires large language models (LLMs) that not only answer questions but also actively gather critical information through well-crafted inquiries. This paper introduces HealthQ, a novel framework for evaluating the questioning capabilities of LLM healthcare chains. By implementing advanced LLM chains, including Retrieval-Augmented Generation (RAG), Chain of Thought (CoT), and reflective chains, HealthQ assesses how effectively these chains elicit comprehensive and relevant patient information. To achieve this, we integrate an LLM judge to evaluate generated questions across metrics such as specificity, relevance, and usefulness, while aligning these evaluations with traditional Natural Language Processing (NLP) metrics like ROUGE and Named Entity Recognition (NER)-based set comparisons. We validate HealthQ using two custom datasets constructed from public medical datasets, ChatDoctor and MTS-Dialog, and demonstrate its robustness across multiple LLM judge models, including GPT-3.5, GPT-4, and Claude. Our contributions are threefold: we present the first systematic framework for assessing questioning capabilities in healthcare conversations, establish a model-agnostic evaluation methodology, and provide empirical evidence linking high-quality questions to improved patient information elicitation. • We introduce HealthQ, the first to evaluate LLM questioning in healthcare chains. • HealthQ integrates RAG, CoT, and reflection to improve patient question quality. • Validated on two medical datasets with gains in specificity and relevance.

Smart HealthVol. 36
Kookmin University (KR), University of California, Irvine (US), Washington University in St. Louis (US), Columbia University (US)
Openalex Percentile: Top 0%
Big Data and Business Intelligence
27.41
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HealthQ: Unveiling questioning capabilities of LLM chains in healthcare conversations — Amir M. Rahmani, Ziyu Wang, et al. · Smart Health (2025) | TGRS Research Map | TGRS