Antibiotic-driven pathogen replacement events in a kidney transplant recipient with ADPKD: a case report
This case highlights the replacement of dominant pathogens under antibiotic selection pressure in polycystic kidney infections, primarily involving gram-negative bacilli. When initial and subsequent antibiotic therapy fail, re-evaluation of the cyst infection definition is necessary, and preemptive native nephrectomy should be considered.
Authors
- Yun Miao (ORCID: https://orcid.org/0000-0003-3592-4695)
- Renfei Xia (ORCID: https://orcid.org/0009-0002-2400-2513)
- Bin Yang
- Jialiang Hui (ORCID: https://orcid.org/0000-0002-9879-9388)
- Ziyan Yan (ORCID: https://orcid.org/0009-0003-5370-1548)
- Wenli Zeng (ORCID: https://orcid.org/0000-0003-3256-1817)
- Yuchen Wang (ORCID: https://orcid.org/0000-0003-3253-5117)
- Jian Xu (ORCID: https://orcid.org/0000-0001-7303-2909)
Institutions
- Nanfang Hospital (CN)
- Vision Medicals (China) (CN)
Publication Details
- Journal
- BMC Infectious Diseases
- Published
- 2025-03-26
- DOI
- https://doi.org/10.1186/s12879-025-10804-x
- Citations
- 1
- Primary Topic
- Genetic and Kidney Cyst Diseases
- Type
- article
- Field-Weighted Citation Impact
- 1.82
Funders
- National Natural Science Foundation of China
- Basic and Applied Basic Research Foundation of Guangdong Province