Investigator-initiated versus industry-sponsored trials – visibility and relevance of randomized controlled trials in clinical practice guidelines (IMPACT)

This study demonstrated that a considerable number of trials previously identified as being linked to CPGs have had impact in those CPGs (85%). International ISTs seem to have a lower impact on CPGs, and fewer of them influence CPGs at all.

Authors

Harald Binder (ORCID: https://orcid.org/0000-0002-5666-8662)
Anette Blümle (ORCID: https://orcid.org/0000-0003-2877-1029)
Nadine Binder (ORCID: https://orcid.org/0000-0002-1919-4154)
Myron Hecht
Martin Schumacher (ORCID: https://orcid.org/0000-0002-5037-0099)

Institutions

University of Freiburg (DE)
University Medical Center Freiburg (DE)

Publication Details

Journal: BMC Medical Research Methodology
Published: 2025-03-26
DOI: https://doi.org/10.1186/s12874-025-02535-z
Citations: 4
Primary Topic: Clinical practice guidelines implementation
Type: article
Field-Weighted Citation Impact: 7.51

Funders

Deutsche Forschungsgemeinschaft

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article

Investigator-initiated versus industry-sponsored trials – visibility and relevance of randomized controlled trials in clinical practice guidelines (IMPACT)

Harald Binder, Anette Blümle, Nadine Binder, Myron Hecht et al.

Mar 26, 2025

4 citations

BMC Medical Research Methodology

Clinical practice guidelines implementation

7.51

article

Investigator-initiated versus industry-sponsored trials – visibility and relevance of randomized controlled trials in clinical practice guidelines (IMPACT)

Harald Binder, Anette Blümle, Nadine Binder, Myron Hecht, Martin Schumacher

March 26, 2025article en

4 citations

Abstract

This study demonstrated that a considerable number of trials previously identified as being linked to CPGs have had impact in those CPGs (85%). International ISTs seem to have a lower impact on CPGs, and fewer of them influence CPGs at all.

BMC Medical Research MethodologyVol. 25(1)

University of Freiburg (DE), University Medical Center Freiburg (DE)

Deutsche Forschungsgemeinschaft

Industry, innovation and infrastructure

Openalex Percentile: Top 3%

Clinical practice guidelines implementation

7.51

DOI Open Access PDF OpenAlex

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Investigator-initiated versus industry-sponsored trials – visibility and relevance of randomized controlled trials in clinical practice guidelines (IMPACT) — Harald Binder, Anette Blümle, et al. · BMC Medical Research Methodology (2025) | TGRS Research Map | TGRS