Mixed mullerian tumour presenting as giant uterine mass: a case report and review of literature

Malignant mixed Müllerian tumors (MMMT) of the uterine corpus, also referred to as uterine carcinosarcomas, are rare and aggressive neoplasms, accounting for only 1–2% of uterine cancers. These tumors exhibit poor prognosis, with a 5-year survival rate of approximately 30% and only 50% being diagnosed at an early stage. Early detection is crucial, and imaging modalities such as computed tomography (CT) and magnetic resonance imaging (MRI) play a critical role in assessing tumor size, metastasis, and infiltration. The standard treatment involves surgical resection combined with platinum-based chemotherapy. Here, we present a rare case of a giant uterine mass in a 67-year-old female, confirmed to be MMMT. The patient underwent surgical debulking followed by chemotherapy, achieving significant resolution as evidenced by imaging. This case highlights the importance of early diagnosis and multimodal treatment in improving outcomes in MMMT.

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Publication Details

Journal
International Surgery Journal
Published
2025-03-26
DOI
https://doi.org/10.18203/2349-2902.isj20250834
Primary Topic
Uterine Myomas and Treatments
Type
article
Field-Weighted Citation Impact
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article

Mixed mullerian tumour presenting as giant uterine mass: a case report and review of literature

V Doshi, Vijay R. Naik, Aparna Joshi, Chitra Nayak et al.
International Surgery Journal
Uterine Myomas and Treatments
article

Mixed mullerian tumour presenting as giant uterine mass: a case report and review of literature

V Doshi, Vijay R. Naik, Aparna Joshi, Chitra Nayak, Bossuet Afonso
article en

Abstract

Malignant mixed Müllerian tumors (MMMT) of the uterine corpus, also referred to as uterine carcinosarcomas, are rare and aggressive neoplasms, accounting for only 1–2% of uterine cancers. These tumors exhibit poor prognosis, with a 5-year survival rate of approximately 30% and only 50% being diagnosed at an early stage. Early detection is crucial, and imaging modalities such as computed tomography (CT) and magnetic resonance imaging (MRI) play a critical role in assessing tumor size, metastasis, and infiltration. The standard treatment involves surgical resection combined with platinum-based chemotherapy. Here, we present a rare case of a giant uterine mass in a 67-year-old female, confirmed to be MMMT. The patient underwent surgical debulking followed by chemotherapy, achieving significant resolution as evidenced by imaging. This case highlights the importance of early diagnosis and multimodal treatment in improving outcomes in MMMT.

International Surgery JournalVol. 12(4)
Voluntary Health Association of Goa (IN)
Openalex Percentile: Top 92%
Uterine Myomas and Treatments
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