Mixed mullerian tumour presenting as giant uterine mass: a case report and review of literature
Malignant mixed Müllerian tumors (MMMT) of the uterine corpus, also referred to as uterine carcinosarcomas, are rare and aggressive neoplasms, accounting for only 1–2% of uterine cancers. These tumors exhibit poor prognosis, with a 5-year survival rate of approximately 30% and only 50% being diagnosed at an early stage. Early detection is crucial, and imaging modalities such as computed tomography (CT) and magnetic resonance imaging (MRI) play a critical role in assessing tumor size, metastasis, and infiltration. The standard treatment involves surgical resection combined with platinum-based chemotherapy. Here, we present a rare case of a giant uterine mass in a 67-year-old female, confirmed to be MMMT. The patient underwent surgical debulking followed by chemotherapy, achieving significant resolution as evidenced by imaging. This case highlights the importance of early diagnosis and multimodal treatment in improving outcomes in MMMT.
Authors
- V Doshi
- Vijay R. Naik
- Aparna Joshi (ORCID: https://orcid.org/0000-0002-7366-177X)
- Chitra Nayak (ORCID: https://orcid.org/0009-0003-1508-9730)
- Bossuet Afonso
Institutions
- Voluntary Health Association of Goa (IN)
Publication Details
- Journal
- International Surgery Journal
- Published
- 2025-03-26
- DOI
- https://doi.org/10.18203/2349-2902.isj20250834
- Primary Topic
- Uterine Myomas and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00