Neurological Outcomes of Joint Exposure to Polystyrene Micro/Nanospheres and Silver Nanoparticles in Zebrafish
Our findings demonstrate that polystyrene nanospheres (PSNPs) intensified AgNPs-induced neurotoxicity in larval zebrafish, whereas polystyrene microspheres (PSMPs) had a lesser effect, indicating distinct gene regulation roles when combined with AgNPs. These findings enhance the assessment of environmental risks in settings with coexisting nanomaterials and microplastics, offering important insights for evaluating combined exposure risks. https://doi.org/10.1289/EHP14873.
Authors
- Qiuhui Qian (ORCID: https://orcid.org/0000-0003-4143-8802)
- Xingcheng Liu (ORCID: https://orcid.org/0000-0003-1836-2205)
- Qian Pu
- Jie Song (ORCID: https://orcid.org/0000-0001-9285-6559)
- Chen Chen (ORCID: https://orcid.org/0000-0001-5902-3037)
- Huili Wang (ORCID: https://orcid.org/0000-0002-1359-9484)
- Xinlei Zhang (ORCID: https://orcid.org/0000-0002-9270-0527)
- Jin Yan
- Zejun Wang (ORCID: https://orcid.org/0009-0000-3497-6106)
- Xuedong Wang (ORCID: https://orcid.org/0000-0002-8343-0692)
Institutions
- Suzhou University of Science and Technology (CN)
Publication Details
- Journal
- Environmental Health Perspectives
- Published
- 2025-03-26
- DOI
- https://doi.org/10.1289/ehp14873
- Citations
- 14
- Primary Topic
- Microplastics and Plastic Pollution
- Type
- article
- Field-Weighted Citation Impact
- 7.05