Neural correlates of frailty in cognitively healthy adults: A multimodal imaging study
The associations between cognitive test scores and anatomical and functional patterns in the brain highlight the complex interconnections between physical and cognitive aspects of frailty. This study brings novel insights into the early neurobiological markers associated with physical frailty in a cognitively healthy population.
Authors
- Dante Mantini (ORCID: https://orcid.org/0000-0001-6485-5559)
- Lorenza Maistrello (ORCID: https://orcid.org/0000-0003-2955-4376)
- Giorgio Arcara (ORCID: https://orcid.org/0000-0001-6270-6883)
- Nicola Filippini (ORCID: https://orcid.org/0000-0003-1513-5269)
- Sonia Montemurro (ORCID: https://orcid.org/0000-0002-8752-0978)
- Ilaria Parrotta (ORCID: https://orcid.org/0009-0001-4633-3818)
- Giovanni Lazzaro (ORCID: https://orcid.org/0009-0000-9304-902X)
Institutions
- University of Padua (IT)
- IRCCS San Camillo Hospital (IT)
- KU Leuven (BE)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-03-26
- DOI
- https://doi.org/10.1371/journal.pone.0320492
- Citations
- 3
- Primary Topic
- Frailty in Older Adults
- Type
- article
- Field-Weighted Citation Impact
- 3.67
Funders
- Ministero della Salute