Physical activity and handgrip strength in patients with mild, moderate and severe haemophilia: Impacts on bone quality and lean mass
PA does not differ significantly between the severity phenotypes. The majority of PwH in all severity phenotypes performed low-impact PA, which is most likely insufficient to positively affect BMD. However, handgrip strength correlates with BMD and TBS. Despite restrictions in movement function or reduced BMD, it is of major importance to promote PA to maintain a healthy or even increase bone quality.
Authors
- Jamil Hmida (ORCID: https://orcid.org/0000-0003-0796-7831)
- Thomas Hilberg (ORCID: https://orcid.org/0000-0002-0935-2526)
- Alexander Schmidt (ORCID: https://orcid.org/0009-0001-5577-7306)
- Marius Brühl (ORCID: https://orcid.org/0009-0006-1325-0510)
- Robert Ossendorff (ORCID: https://orcid.org/0000-0002-6636-8065)
- Pia Ransmann (ORCID: https://orcid.org/0000-0002-8466-5389)
- Andreas Christian Strauss (ORCID: https://orcid.org/0000-0001-7777-3253)
- Frank Alexander Schildberg (ORCID: https://orcid.org/0000-0003-0797-1945)
- Johannes Oldenburg (ORCID: https://orcid.org/0000-0002-1585-4100)
- Georg Goldmann
- Fabian Tomschi (ORCID: https://orcid.org/0000-0003-1738-4891)
Institutions
- University of Wuppertal (DE)
- University Hospital Bonn (DE)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-03-26
- DOI
- https://doi.org/10.1371/journal.pone.0319951
- Citations
- 4
- Primary Topic
- Hemophilia Treatment and Research
- Type
- article
- Field-Weighted Citation Impact
- 7.08
Funders
- Bayer Vital