Interactome of the oncogenic ΔNp73α isoform in human papillomavirus 38 E6/E7-transformed keratinocytes

ΔNp73α is a major oncogenic isoform of tumor suppressor p73. Here, we report ΔNp73α protein-binding partners in the organelle and cytoplasmic compartments of a cellular model consisting of human keratinocytes transformed by the E6 and E7 oncoproteins of the β-HPV38 virus associated with non-melanoma skin cancer.

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Publication Details

Journal
Microbiology Resource Announcements
Published
2025-03-26
DOI
https://doi.org/10.1128/mra.01071-24
Primary Topic
Cancer-related Molecular Pathways
Type
article
Field-Weighted Citation Impact
0.00

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article

Interactome of the oncogenic ΔNp73α isoform in human papillomavirus 38 E6/E7-transformed keratinocytes

Katia Zanier, Valério Taverniti, Luc Négroni, Massimo Tommasino
Microbiology Resource Announcements
Cancer-related Molecular Pathways
article

Interactome of the oncogenic ΔNp73α isoform in human papillomavirus 38 E6/E7-transformed keratinocytes

Katia Zanier, Valério Taverniti, Luc Négroni, Massimo Tommasino
article en

Abstract

ΔNp73α is a major oncogenic isoform of tumor suppressor p73. Here, we report ΔNp73α protein-binding partners in the organelle and cytoplasmic compartments of a cellular model consisting of human keratinocytes transformed by the E6 and E7 oncoproteins of the β-HPV38 virus associated with non-melanoma skin cancer.

Microbiology Resource AnnouncementsVol. 14(4)
Inserm (FR), Institut de génétique et de biologie moléculaire et cellulaire (FR), World Health Organization (CH), École Supérieure de Biotechnologie de Strasbourg (FR), Biotechnologie et Signalisation Cellulaire (FR), Centre international de recherche sur le cancer (FR), Université de Strasbourg (FR)
Agence Nationale de la Recherche, Institut National de la Santé et de la Recherche Médicale, Fondation pour la Recherche Médicale, Institut National Du Cancer
Good health and well-being
Openalex Percentile: Top 92%
Cancer-related Molecular Pathways
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