Features of oncolytic virotherapy and its application for the treatment of glioblastoma

Oncolytic virotherapy is a promising treatment method that uses viruses to destroy cancer cells. This approach is particularly interesting in the context of the treatment of glioblastoma, one of the most aggressive forms of brain tumors. This therapy is based on the use of modified viruses capable of purposefully infecting and destroying tumor cells, while minimally affecting healthy tissues. The features of oncolytic virotherapy are the high specificity of viruses to cancer cells, which contributes to the activation of the body's immune response and increases therapeutic effectiveness. The use of oncolytic virotherapy for the treatment of glioblastoma is already yielding encouraging results in clinical trials and may be an important addition to traditional treatments such as surgery, radiotherapy and chemotherapy. In conclusion, oncolytic virotherapy is a promising approach to the treatment of glioblastoma, which requires further study to better understand its mechanisms of action and optimize its use in clinical practice.

Authors

Publication Details

Journal
Clinical review for general practice
Published
2024-12-26
DOI
https://doi.org/10.47407/kr2024.5.12.00537
Citations
1
Primary Topic
Virus-based gene therapy research
Type
article
Field-Weighted Citation Impact
0.55
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article

Features of oncolytic virotherapy and its application for the treatment of glioblastoma

Vitalii B. Kaliberdenko, Ernest E. Aramyan, Maksim S. Zinchenko
1 citations
Clinical review for general practice
Virus-based gene therapy research
0.55
article

Features of oncolytic virotherapy and its application for the treatment of glioblastoma

Vitalii B. Kaliberdenko, Ernest E. Aramyan, Maksim S. Zinchenko
article en
1 citations

Abstract

Oncolytic virotherapy is a promising treatment method that uses viruses to destroy cancer cells. This approach is particularly interesting in the context of the treatment of glioblastoma, one of the most aggressive forms of brain tumors. This therapy is based on the use of modified viruses capable of purposefully infecting and destroying tumor cells, while minimally affecting healthy tissues. The features of oncolytic virotherapy are the high specificity of viruses to cancer cells, which contributes to the activation of the body's immune response and increases therapeutic effectiveness. The use of oncolytic virotherapy for the treatment of glioblastoma is already yielding encouraging results in clinical trials and may be an important addition to traditional treatments such as surgery, radiotherapy and chemotherapy. In conclusion, oncolytic virotherapy is a promising approach to the treatment of glioblastoma, which requires further study to better understand its mechanisms of action and optimize its use in clinical practice.

Clinical review for general practiceVol. 5(12)
Openalex Percentile: Top 23%
Virus-based gene therapy research
0.55
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Features of oncolytic virotherapy and its application for the treatment of glioblastoma — Vitalii B. Kaliberdenko, Ernest E. Aramyan, et al. · Clinical review for general practice (2024) | TGRS Research Map | TGRS