Recurrence of schizophreniform psychosis, coincident with the detection of ovarian tumors. The case of 30-year-old patient

The article presents a unique clinical case of 30-year-old patient G. Over the course of eight years, the patient suffered two psychotic episodes with schizophreniform symptoms – the first was dominated by affective-delusional symptoms, and the second was catatonic. Each time, psychosis occurred against the background of elevated body temperature. Initially, she was diagnosed with schizophrenia, for which she underwent psychopharmacotherapy with antipsychotics. At the second time, the neuropsychiatric condition was considered to be related to seronegative anti-NMDA receptor encephalitis and she received hormonal therapy. During the interictal period, G. led an active lifestyle, was socially adapted, and did not exhibit any psychotic symptoms. The peculiarity of her condition was that during the first episode she was diagnosed with a cystadenoma of the right ovary, and 8 years before the second episode she was diagnosed with a teratoma of the left ovary. In addition, according to relatives, recovery after the first attack of the disease coincided with the radical gynecological operation performed (right-sided oophorectomy), and the lack of significant improvement during the second psychotic episode was associated with an insufficient amount of surgical intervention for teratoma of the left ovary (resection). At the time of this examination of patient G., it was not possible to draw an unambiguous conclusion that her mental disorder had common pathogenetic mechanisms. Further observation will allow us to make a more convincing diagnostic conclusion.