Effect of tofacitinib exposure <i>in utero and during breastfeeding</i> on the immune status of exposed child
This case suggests that prolonged prenatal and postnatal exposure to tofacitinib may not adversely affect infant immune development. However, caution is advised due to the limited number of documented cases. Further research is needed to fully understand the long-term implications of JAK inhibitor exposure during pregnancy and breastfeeding.
Authors
- Milan Lukáš (ORCID: https://orcid.org/0000-0002-1463-3840)
- Katarína Mitrová (ORCID: https://orcid.org/0000-0002-1836-3745)
- Marta Kostrejová
- Kristýna Zdychyncová
- Duricova Dana
Institutions
- Charles University (CZ)
- Iscare I.V.F (CZ)
- Sisters of Mercy Health System (US)
- Institute of Clinical and Experimental Medicine (CZ)
Publication Details
- Journal
- Journal of Crohn s and Colitis
- Published
- 2025-03-24
- DOI
- https://doi.org/10.1093/ecco-jcc/jjaf049
- Citations
- 2
- Primary Topic
- Pregnancy and Medication Impact
- Type
- article
- Field-Weighted Citation Impact
- 3.76