Microscope‐Assisted Hypertensive Retinopathy Diagnosis Using Deep Learning Models

The retina is the most crucial part of the human eye, and it can be affected due to hypertension. However, retinal abnormalities due to hypertension are termed hypertensive retinopathy (HR). A severe stage of HR can lead to complete blindness if not diagnosed and treated on time. Manually analyzing retinal images for HR diagnosis is time-consuming and prone to errors. This research article provides a novel technique based on U-Net and Dense-Net for automatic HR detection and grading through retinal images. The presented method consists of preprocessing, vessel segmentation, artery or vein (A/V) classification, and vessel width calculation to compute the arteriovenous ratio (AVR). In the preprocessing phase, the Gabor filter is applied to the retinal image to enhance the vascular network of the image. The preprocessed image is fed into the U-Net architecture to segment the vascular network image. The segmented vascular network image is fed into the Dense-Net architecture for A/V classification. The A/V classified vascular network is divided into several artery and vein segments at the bifurcation and crossover points. The A/V segments are labeled for width calculation to compute the AVR. The AVR is a standard parameter for HR detection and grading. The evaluation results show an average accuracy of 99.40% in HR classification and 99.77% in HR grading on the AVRDB dataset. The evaluated results are beneficial for the automatic HR detection and grading for clinical purposes.

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Publication Details

Journal
Microscopy Research and Technique
Published
2025-03-24
DOI
https://doi.org/10.1002/jemt.24847
Primary Topic
Retinal Imaging and Analysis
Type
article
Field-Weighted Citation Impact
0.00

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article

Microscope‐Assisted Hypertensive Retinopathy Diagnosis Using Deep Learning Models

Shahzad Akbar, Saad Khan, Faten S. Alamri, Tanzila Saba et al.
Microscopy Research and Technique
Retinal Imaging and Analysis
article

Microscope‐Assisted Hypertensive Retinopathy Diagnosis Using Deep Learning Models

Shahzad Akbar, Saad Khan, Faten S. Alamri, Tanzila Saba, Amjad Rehman Khan, Usama Shahzore
article en

Abstract

The retina is the most crucial part of the human eye, and it can be affected due to hypertension. However, retinal abnormalities due to hypertension are termed hypertensive retinopathy (HR). A severe stage of HR can lead to complete blindness if not diagnosed and treated on time. Manually analyzing retinal images for HR diagnosis is time-consuming and prone to errors. This research article provides a novel technique based on U-Net and Dense-Net for automatic HR detection and grading through retinal images. The presented method consists of preprocessing, vessel segmentation, artery or vein (A/V) classification, and vessel width calculation to compute the arteriovenous ratio (AVR). In the preprocessing phase, the Gabor filter is applied to the retinal image to enhance the vascular network of the image. The preprocessed image is fed into the U-Net architecture to segment the vascular network image. The segmented vascular network image is fed into the Dense-Net architecture for A/V classification. The A/V classified vascular network is divided into several artery and vein segments at the bifurcation and crossover points. The A/V segments are labeled for width calculation to compute the AVR. The AVR is a standard parameter for HR detection and grading. The evaluation results show an average accuracy of 99.40% in HR classification and 99.77% in HR grading on the AVRDB dataset. The evaluated results are beneficial for the automatic HR detection and grading for clinical purposes.

Microscopy Research and TechniqueVol. 88(8)
Princess Nourah bint Abdulrahman University (SA), Prince Sultan University (SA), Shandong University (CN), Riphah International University (PK), University of Jinan (CN)
Princess Nourah Bint Abdulrahman University
Good health and well-being
Openalex Percentile: Top 91%
Retinal Imaging and Analysis
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