Shielding resources for four common radiopharmaceuticals utilized for imaging and therapy: Tc‐99m, F‐18, I‐131, and Lu‐177

While Lu-177 has a relatively low exposure rate constant, shielding may be necessary for high-volume therapies like Lu-177 DOTATATE and Lu-177 vipivotide tetraxetan PSMA. Shielding involves accounting for broad radiation beams and requires thorough characterization of radiation buildup. When shielding to the typical height of 7 feet, scatter from ceilings and floors is negligible for transmission above 10%, but severely limits the ability to shield for transmission below 1%.

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Publication Details

Journal
Journal of Applied Clinical Medical Physics
Published
2025-03-24
DOI
https://doi.org/10.1002/acm2.70084
Primary Topic
Advanced Radiotherapy Techniques
Type
article
Field-Weighted Citation Impact
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article

Shielding resources for four common radiopharmaceuticals utilized for imaging and therapy: Tc‐99m, F‐18, I‐131, and Lu‐177

K. Matthews, Sharon L. White, James Botti, Kevin J. Little et al.
Journal of Applied Clinical Medical Physics
Advanced Radiotherapy Techniques
article

Shielding resources for four common radiopharmaceuticals utilized for imaging and therapy: Tc‐99m, F‐18, I‐131, and Lu‐177

K. Matthews, Sharon L. White, James Botti, Kevin J. Little, R J Massoth, Nathan Busse, Michael Oumano, David E. Hintenlang, Rameshwar Prasad, Stephanie Leon, Melissa Martin, J. Clancy Clements, Richard E. Wendt
article en

Abstract

While Lu-177 has a relatively low exposure rate constant, shielding may be necessary for high-volume therapies like Lu-177 DOTATATE and Lu-177 vipivotide tetraxetan PSMA. Shielding involves accounting for broad radiation beams and requires thorough characterization of radiation buildup. When shielding to the typical height of 7 feet, scatter from ceilings and floors is negligible for transmission above 10%, but severely limits the ability to shield for transmission below 1%.

Journal of Applied Clinical Medical PhysicsVol. 26(5)
Louisiana State University (US), The University of Texas MD Anderson Cancer Center (US), Brown University (US), Rhode Island Hospital (US), University of Vermont Medical Center (US), University of Alabama at Birmingham (US), University of Florida (US), Landauer (United States) (US), American University of Health Sciences (US), Southwestern Medical Center (US), Medical Physics Consultants (US), Southwestern Medical Center (US), The Ohio State University (US), The University of Texas Southwestern Medical Center (US)
Openalex Percentile: Top 93%
Advanced Radiotherapy Techniques
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Shielding resources for four common radiopharmaceuticals utilized for imaging and therapy: Tc‐99m, F‐18, I‐131, and Lu‐177 — K. Matthews, Sharon L. White, et al. · Journal of Applied Clinical Medical Physics (2025) | TGRS Research Map | TGRS