Multiple cell-type interactions drive invariant NKT cell hepatitis
Neutrophil and macrophage infiltration through multiple inflammatory mediators is required for NKT cell activation-induced hepatitis, which sheds light on the myeloid cell infiltration-related molecular mechanisms of NKT cell-mediated liver injury. Our study may provide a novel therapeutical strategy for the treatment of NKT cell hepatitis.
Authors
- Weidong Zhao (ORCID: https://orcid.org/0000-0002-4444-6595)
- Longshan Ji (ORCID: https://orcid.org/0000-0003-3588-5868)
- Yueqiu Gao (ORCID: https://orcid.org/0000-0001-7276-9810)
- Ruowen Guo (ORCID: https://orcid.org/0000-0003-0612-6803)
- Yong He (ORCID: https://orcid.org/0000-0003-4062-9201)
- Yawen Hao
- Jiaxin Tan (ORCID: https://orcid.org/0009-0000-1460-1868)
- Qiuhong Zai
- Qian Li (ORCID: https://orcid.org/0000-0003-0359-5604)
- Man Li (ORCID: https://orcid.org/0000-0002-6754-143X)
- Xuewei Zhang (ORCID: https://orcid.org/0000-0003-4512-1335)
- Miao Fang (ORCID: https://orcid.org/0000-0002-0924-8323)
- Peng Xiao (ORCID: https://orcid.org/0000-0002-8994-8433)
- Yanhang Gao (ORCID: https://orcid.org/0000-0002-7033-8491)
- Yating Gao (ORCID: https://orcid.org/0000-0002-5309-7243)
- Xin Zhang (ORCID: https://orcid.org/0000-0001-6036-2685)
Institutions
- Jilin University (CN)
- Chinese Academy of Sciences (CN)
- Shanghai University of Traditional Chinese Medicine (CN)
- Shanghai Institute of Materia Medica (CN)
- First Hospital of Jilin University (CN)
- Shuguang Hospital (CN)
- University of Chinese Academy of Sciences (CN)
- China Medical University (CN)
Publication Details
- Journal
- Hepatology Communications
- Published
- 2025-03-24
- DOI
- https://doi.org/10.1097/hc9.0000000000000592
- Primary Topic
- Immune Cell Function and Interaction
- Type
- article
- Field-Weighted Citation Impact
- 0.00