Impaired accuracy of the dexamethasone suppression test after bariatric surgery: implications for post-surgical cortisol interpretation

Post-BS subjects showed higher post-DST cortisol levels and reached lower plasma dexamethasone concentration compared to non-operated individuals, which may lead to false-positive results. These findings highlight the need to consider dexamethasone measurements to enhance DST interpretation in post-BS patients. Further studies are necessary to validate these findings in broader populations. The underlying mechanisms need to be explored.

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Publication Details

Journal
European Journal of Endocrinology
Published
2025-03-25
DOI
https://doi.org/10.1093/ejendo/lvaf053
Citations
2
Primary Topic
Hormonal Regulation and Hypertension
Type
article
Field-Weighted Citation Impact
2.59
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article

Impaired accuracy of the dexamethasone suppression test after bariatric surgery: implications for post-surgical cortisol interpretation

Marina Giralt, Noelia Díaz‐Troyano, Anna Casteràs, Alba Zabalegui et al.
2 citations
European Journal of Endocrinology
Hormonal Regulation and Hypertension
2.59
article

Impaired accuracy of the dexamethasone suppression test after bariatric surgery: implications for post-surgical cortisol interpretation

Marina Giralt, Noelia Díaz‐Troyano, Anna Casteràs, Alba Zabalegui, Enzamaría Fidilio, Marta Comas, Ramón Vilallonga, Roser Ferrer, Betina Biagetti, Andreea Ciudin, Vanesa Flores
article en
2 citations

Abstract

Post-BS subjects showed higher post-DST cortisol levels and reached lower plasma dexamethasone concentration compared to non-operated individuals, which may lead to false-positive results. These findings highlight the need to consider dexamethasone measurements to enhance DST interpretation in post-BS patients. Further studies are necessary to validate these findings in broader populations. The underlying mechanisms need to be explored.

European Journal of EndocrinologyVol. 192(4)
Universitat Autònoma de Barcelona (ES), Vall d'Hebron Institut de Recerca (ES), Vall d'Hebron Hospital Universitari (ES)
Good health and well-being
Openalex Percentile: Top 11%
Hormonal Regulation and Hypertension
2.59
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