Bactericidal activity of antibiotic combinations against clinical isolates of <i>Enterococcus gallinarum</i> and <i>Enterococcus casseliflavus</i>
These data suggest that the ampicillin plus gentamicin combination is frequently synergistic and typically bactericidal and may be the preferred treatment option for endovascular infection caused by E. gallinarum or E. casseliflavus. In contrast to the findings for Enterococcus faecalis, ampicillin plus ceftriaxone is generally not synergistic or bactericidal and thus may not be as effective.
Authors
- Jacob Strahilevitz (ORCID: https://orcid.org/0000-0002-9192-7164)
- Ayelet Michael-Gayego
- Meir Cherniak
- Orit Gefen (ORCID: https://orcid.org/0000-0001-7638-4731)
- David Landman
- Yair Motro (ORCID: https://orcid.org/0000-0003-1289-6919)
- Jacob Moran‐Gilad (ORCID: https://orcid.org/0000-0001-9134-050X)
Institutions
- Ben-Gurion University of the Negev (IL)
- Hebrew University of Jerusalem (IL)
- FZU ‒ Institute of Physics of the Academy of Sciences of the Czech Republic (CZ)
Publication Details
- Journal
- Journal of Antimicrobial Chemotherapy
- Published
- 2025-03-25
- DOI
- https://doi.org/10.1093/jac/dkaf095
- Citations
- 2
- Primary Topic
- Infective Endocarditis Diagnosis and Management
- Type
- article
- Field-Weighted Citation Impact
- 2.71