Depletion of tumor-reactive HSCs reveals their significance during different stages of liver metastasis
Depletion of tumor-reactive proliferating HSCs implicates these cells as the required spark for the initiation and progression of liver metastasis, making them a good candidate for new therapies targeting the tumor microenvironment to treat liver metastasis of different primary origins.
Authors
- María Dolores Boyano (ORCID: https://orcid.org/0000-0001-6051-1054)
- Alba Herrero (ORCID: https://orcid.org/0000-0002-7436-1605)
- Aritz Lopategi (ORCID: https://orcid.org/0000-0001-6501-1788)
- Beatriz Arteta (ORCID: https://orcid.org/0000-0003-3253-3162)
- Scott L. Friedman (ORCID: https://orcid.org/0000-0003-1178-6195)
- Aitor Benedicto (ORCID: https://orcid.org/0000-0002-3026-7190)
Institutions
- University of the Basque Country (ES)
- Icahn School of Medicine at Mount Sinai (US)
Publication Details
- Journal
- Hepatology Communications
- Published
- 2025-03-24
- DOI
- https://doi.org/10.1097/hc9.0000000000000669
- Citations
- 2
- Primary Topic
- Liver physiology and pathology
- Type
- article
- Field-Weighted Citation Impact
- 2.64