Efficacy and Safety of WXSH0208 Tablets in Treatment of Acute Uncomplicated Influenza Infection in Adults: A Multicenter Randomized, Double-Blind, Placebo-Controlled Phase 2 Trial
WXSH0208 showed no evident safety concerns and was superior to placebo in reducing viral load in adult outpatients with uncomplicated influenza. Clinical Trials Registration. CTR20233250 (www.chinadrugtrials.org.cn).
Authors
- Wenhao Cao (ORCID: https://orcid.org/0000-0003-2483-8775)
- Jianqing Zhao (ORCID: https://orcid.org/0000-0001-9540-3133)
- Fei Shi (ORCID: https://orcid.org/0000-0002-9082-9140)
- Gang He (ORCID: https://orcid.org/0000-0001-9806-4069)
- Zhiang Huang
- Lijun Suo (ORCID: https://orcid.org/0000-0002-4847-5289)
- Weihua Su (ORCID: https://orcid.org/0009-0001-2247-9900)
- Xinyu Song (ORCID: https://orcid.org/0000-0002-4911-1903)
- Shuchun Gao (ORCID: https://orcid.org/0009-0008-7811-6966)
- Haiying Yan (ORCID: https://orcid.org/0009-0000-6336-8249)
- Kuan Liu (ORCID: https://orcid.org/0000-0002-1006-2198)
- Yi Gao (ORCID: https://orcid.org/0000-0003-1086-6564)
- Liyu Li (ORCID: https://orcid.org/0000-0002-6675-6009)
- Jinxiang Wang (ORCID: https://orcid.org/0000-0002-2888-6742)
- Xiao Liu (ORCID: https://orcid.org/0000-0003-4221-5061)
- Jie Li (ORCID: https://orcid.org/0000-0002-7529-6040)
- Bin Cao (ORCID: https://orcid.org/0000-0001-6991-0350)
- Lingling Ma
- Tianhao Li (ORCID: https://orcid.org/0000-0001-9500-6584)
- Yeming Wang (ORCID: https://orcid.org/0000-0003-4343-9606)
- Yongzhong Li (ORCID: https://orcid.org/0000-0002-1086-1598)
- Hong Zhao (ORCID: https://orcid.org/0000-0001-8991-7824)
- Jun Yang (ORCID: https://orcid.org/0000-0002-4965-2929)
- Yu Zhang (ORCID: https://orcid.org/0009-0005-2457-2876)
- Rong Qiu (ORCID: https://orcid.org/0009-0003-7516-7876)
Institutions
- Huaihua University (CN)
- University of Electronic Science and Technology of China (CN)
- Harbin Medical University (CN)
- Hebei North University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- China-Japan Friendship Hospital (CN)
- Daqing City People's Hospital (CN)
- Xian Central Hospital (CN)
- Second Affiliated Hospital of Guangzhou Medical University (CN)
- The Fourth People's Hospital of Zibo City (CN)
- Suizhou Central Hospital (CN)
- First Affiliated Hospital of Guangzhou Medical University (CN)
- ShenZhen People’s Hospital (CN)
- Beijing Luhe Hospital Affiliated to Capital Medical University (CN)
- Shandong Provincial Hospital (CN)
- Tianjin Fourth Central Hospital (CN)
- Chengdu Fifth People's Hospital (CN)
- First Affiliated Hospital of Gannan Medical University (CN)
- Nanyang Medical College (CN)
- Affiliated Hospital of Shaanxi University of Chinese Medicine (CN)
- Jiangmen Central Hospital (CN)
- Central Hospital of Zibo (CN)
- Yichang Central People's Hospital (CN)
- First Affiliated Hospital of Henan University (CN)
- Loudi Central Hospital (CN)
- Luoyang Institute of Science and Technology (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- The Journal of Infectious Diseases
- Published
- 2025-03-22
- DOI
- https://doi.org/10.1093/infdis/jiaf075
- Citations
- 1
- Primary Topic
- Influenza Virus Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.35