Changes to Average Survival of Patients With Amyotrophic Lateral Sclerosis (1995–2018)
In the PARALS, ALS survival increased over time. In a subset analysis, the beneficial effect of the epoch was only evident among intermediate progressors. The improvement in multidisciplinary care provided by tertiary centers may be one possible explanation for this finding, although further dedicated studies are needed to confirm this hypothesis.
Authors
- Stefano Callegaro (ORCID: https://orcid.org/0009-0005-2427-2267)
- Fabiola De Marchi (ORCID: https://orcid.org/0000-0003-4366-0167)
- Paolina Salamone (ORCID: https://orcid.org/0000-0001-9038-7816)
- Antonio Canosa (ORCID: https://orcid.org/0000-0001-5876-4079)
- Grazia Zocco
- Enrico Matteoni (ORCID: https://orcid.org/0009-0008-2963-8821)
- Andrea Calvo (ORCID: https://orcid.org/0000-0002-5122-7243)
- Umberto Manera (ORCID: https://orcid.org/0000-0002-9995-8133)
- Sara Cabras (ORCID: https://orcid.org/0000-0002-4988-2855)
- Maurizio Grassano (ORCID: https://orcid.org/0000-0001-6714-6897)
- Barbara Iazzolino (ORCID: https://orcid.org/0000-0001-5748-9175)
- Rosario Vasta (ORCID: https://orcid.org/0000-0002-0393-4736)
- Filippo De Mattei
- Francesca Palumbo (ORCID: https://orcid.org/0000-0002-7070-2409)
- Giorgio Pellegrino
- Cristina Moglia (ORCID: https://orcid.org/0000-0001-7377-7222)
- Francesca Di Pede (ORCID: https://orcid.org/0000-0001-8959-0614)
- Adriano Chiò (ORCID: https://orcid.org/0000-0001-9579-5341)
- Giuseppe Fuda
- Letizia Mazzini
- Emilio Minerva
- Daniela Pascariu
- Salvatore Tafaro
Institutions
- Università di Camerino (IT)
- Università degli Studi del Piemonte Orientale “Amedeo Avogadro” (IT)
- Azienda Ospedaliera Citta' della Salute e della Scienza di Torino (IT)
- Azienda Ospedaliero Universitaria Maggiore della Carita (IT)
- National Research Council (IT)
- Institute of Cognitive Sciences and Technologies (IT)
- University of Turin (IT)
Publication Details
- Journal
- Neurology
- Published
- 2025-03-26
- DOI
- https://doi.org/10.1212/wnl.0000000000213467
- Citations
- 10
- Primary Topic
- Amyotrophic Lateral Sclerosis Research
- Type
- article
- Field-Weighted Citation Impact
- 13.89