Kunxinning granules alleviate perimenopausal syndrome by supplementing estrogen deficiency
This study shows that KXN could relieve anxiety, depression, and osteoporosis in PMS. This pharmacological effect is exerted through steroid hormone synthesis to address estrogen deficiency. The findings provide valuable insights into the underlying mechanisms and support its clinical application.
Authors
- Wen Yang (ORCID: https://orcid.org/0000-0003-2314-400X)
- Yunjuan Li
- Wenshuang Wang
- Man Zhang (ORCID: https://orcid.org/0000-0003-2834-0173)
- Fuhong Wang (ORCID: https://orcid.org/0009-0001-5593-5191)
- Gang Bai (ORCID: https://orcid.org/0000-0001-9161-2173)
- Kaixin Liu (ORCID: https://orcid.org/0000-0001-6778-1591)
- Zhou Gui-rong
- Jinling Zhang (ORCID: https://orcid.org/0000-0003-0482-5432)
- Yuanyuan Hou
- He Gao
Institutions
- Nankai University (CN)
- Tasly Holding Group (China) (CN)
- State Key Laboratory of Medicinal Chemical Biology
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-03-26
- DOI
- https://doi.org/10.3389/fphar.2025.1554479
- Citations
- 3
- Primary Topic
- Medicinal Plant Pharmacodynamics Research
- Type
- article
- Field-Weighted Citation Impact
- 4.67
Funders
- Nankai University
- Fundamental Research Funds for the Central Universities