Multi‐Omic Insight Into the Molecular Networks in the Pathogenesis of Coronary Artery Disease
Our findings provide multi-omics evidence suggesting that <i>TAGLN2</i>, <i>APOB</i>, <i>GIP</i>, <i>DHX58</i>, and <i>SWAP70</i> genes are associated with CAD risk. This work provides novel insights into the molecular mechanisms of CAD and highlights the potential of integrating multi-omics data to uncover potential causal relationships that cannot be fully captured by traditional genome-wide association studies.
Authors
- Hong-Dan Fan
- Jianlin Du (ORCID: https://orcid.org/0000-0001-9349-2435)
- Jing Huang (ORCID: https://orcid.org/0000-0003-2090-5686)
- Qinghua Fang
- Qiaoqiao Li (ORCID: https://orcid.org/0000-0002-1932-0210)
- Muzi Zhang (ORCID: https://orcid.org/0000-0001-8000-1609)
- Zhengzhong Zhou
Institutions
- Dalian Medical University (CN)
- Second Affiliated Hospital of Chongqing Medical University (CN)
- Chongqing Medical University (CN)
Publication Details
- Journal
- Journal of the American Heart Association
- Published
- 2025-03-26
- DOI
- https://doi.org/10.1161/jaha.124.037203
- Citations
- 5
- Primary Topic
- Genetic Associations and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 9.09