Multi-omics pan-cancer analysis reveals the diagnostic and prognostic value of C8orf76, with experimental validation of its impact on lung adenocarcinoma cell proliferation
The present study is the first to report that the multi-omics pan-cancer analysis predicts C8orf76 as a promising target in cancer prognosis, diagnosis, immunology, and chemotherapy, highlighting its influence on cell proliferation in LUAD with experimental validation.
Authors
- Shifang Li
- Yanjiao Hou
- Rongjing Gao
- Miao Zhang (ORCID: https://orcid.org/0000-0002-4421-7100)
- Zhiyong Zhang (ORCID: https://orcid.org/0000-0001-9753-0873)
- Jie Fang (ORCID: https://orcid.org/0000-0003-2545-604X)
- Shiqi Ren (ORCID: https://orcid.org/0009-0004-5800-0166)
- Xiaohong Zhong (ORCID: https://orcid.org/0000-0002-0329-3684)
Institutions
- Qilu Hospital of Shandong University (CN)
- Dezhou University (CN)
Publication Details
- Journal
- Frontiers in Genetics
- Published
- 2025-03-26
- DOI
- https://doi.org/10.3389/fgene.2025.1524422
- Citations
- 1
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 1.52
Funders
- National Natural Science Foundation of China