Assessment of minimum clinically important difference in symptoms and functionality of Japanese patients with major depressive disorder following inadequate response to antidepressants: a post hoc analysis of the long-term study of brexpiprazole augm

The MCIDs for the MADRS, SDS, and EQ-5D-5L -derived utility scores were estimated. Physicians focus more on depressive symptoms and prioritize symptom severity over improvements in functionality and activities of daily life, in contrast to patients, who prioritize such improvements.