Pregnancy Antitissue Transglutaminase Immunoglobulin A Seropositivity and Maternal and Infant Health in the Child Health and Development Studies
tTG-IgA seropositivity was associated with the presence of 2 or more markers of celiac comorbidity. Offspring exposed to maternal seropositivity had poorer fetal growth and lower infant weight gain. Findings support the potential beneficial role of tTG-IgA screening during pregnancy, both for the pregnant woman and exposed offspring.
Authors
- Kartik K. Venkatesh (ORCID: https://orcid.org/0000-0002-8043-556X)
- Piera M. Cirillo (ORCID: https://orcid.org/0000-0003-4571-4544)
- Alessio Fasano (ORCID: https://orcid.org/0000-0002-2134-0261)
- Susan Flaherty (ORCID: https://orcid.org/0000-0002-5153-0218)
- Kajal Sangal
- Lauren Zimmermann
- Barbara A. Cohn (ORCID: https://orcid.org/0000-0002-9912-8447)
- Rajitha Devadoss Venkatesh (ORCID: https://orcid.org/0009-0004-5750-4928)
- Nickilou Y. Krigbaum (ORCID: https://orcid.org/0000-0001-5034-7991)
- Jennifer J. Iscol
Institutions
- Nationwide Children's Hospital (US)
- Community Foundation (US)
- Mead Johnson (United States) (US)
- The Ohio State University Wexner Medical Center (US)
- Massachusetts General Hospital (US)
- Public Health Institute (US)
- Eye Care Associates (US)
- The Ohio State University (US)
Publication Details
- Journal
- The American Journal of Gastroenterology
- Published
- 2025-03-25
- DOI
- https://doi.org/10.14309/ajg.0000000000003424
- Primary Topic
- Celiac Disease Research and Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00