High concordance of human immunodeficiency virus-1 genotypic drug resistance generated from paired cerebrospinal fluid and plasma in antiretroviral therapy -naive or -experienced patients
A high concordance of HIV-1 DRMs between CSF and plasma samples was observed. No unique mutations were identified in CSF other than those in plasma, indicating that the mutant variants in CSF were derived from blood.
Authors
- Linghua Li (ORCID: https://orcid.org/0000-0001-5711-8681)
- Yingfen Wen (ORCID: https://orcid.org/0000-0002-3545-7911)
- Xizi Deng
- Yaqing Lin
- Yun Lan (ORCID: https://orcid.org/0000-0002-9783-4268)
- Fengyu Hu (ORCID: https://orcid.org/0000-0002-8649-7913)
- Jiaojiao Li
- Liya Li (ORCID: https://orcid.org/0000-0003-3255-6663)
- Ruiying He
- Xuemei Ling
Institutions
- Guangzhou Eighth People's Hospital (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- Frontiers in Microbiology
- Published
- 2025-03-26
- DOI
- https://doi.org/10.3389/fmicb.2025.1518225
- Primary Topic
- HIV Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00