Recurrent Stroke Prediction by Applying a Stroke Polygenic Risk Score in the Japanese Population
The metaGRS developed in a Japanese cohort predicted stroke recurrence in an independent cohort of patients. In particular, it predicted an increased risk of recurrence among stroke patients without hypertension. These findings provide clues for additional genetic risk stratification and help in developing personalized strategies for stroke recurrence prevention.
Authors
- N. Kojima (ORCID: https://orcid.org/0009-0001-2656-6833)
- Masaru Koido (ORCID: https://orcid.org/0000-0002-0348-0666)
- Yoichiro Kamatani (ORCID: https://orcid.org/0000-0001-8748-5597)
- Tsuyoshi Hachiya (ORCID: https://orcid.org/0000-0002-5274-3266)
- Stéphanie Debette (ORCID: https://orcid.org/0000-0001-8675-7968)
- Yunye He (ORCID: https://orcid.org/0000-0001-8581-7826)
- Yuka Shimmori
Institutions
- Université de Bordeaux (FR)
- Inserm (FR)
- Institut des Maladies Neurodégénératives (FR)
- Bordeaux Population Health (FR)
- YKK (Japan) (JP)
Publication Details
- Journal
- Stroke
- Published
- 2025-03-26
- DOI
- https://doi.org/10.1161/strokeaha.124.047786
- Citations
- 1
- Primary Topic
- Genetic Associations and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 1.82