Effect and mechanism of Plantaginis Semen polysaccharides on intestinal microecology in rats with hyperuricemia

In summary, the present study substantiates the therapeutic potential of PSP in treating hyperuricemia through its dual action of lowering uric acid levels and imparting anti-inflammatory effects. The observed modulation of gut microbiota further supports the role of PSP in maintaining metabolic homeostasis. Future investigations should focus on the clinical applicability of PSP and elucidate the mechanisms underlying its beneficial impacts on hyperuricemia and associated metabolic disorders.

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Publication Details

Journal
Frontiers in Microbiology
Published
2025-03-26
DOI
https://doi.org/10.3389/fmicb.2025.1555734
Citations
5
Primary Topic
Gout, Hyperuricemia, Uric Acid
Type
article
Field-Weighted Citation Impact
7.15
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article

Effect and mechanism of Plantaginis Semen polysaccharides on intestinal microecology in rats with hyperuricemia

Yu Fu, Hongbin Qiu, Jing Zhao
5 citations
Frontiers in Microbiology
Gout, Hyperuricemia, Uric Acid
7.15
article

Effect and mechanism of Plantaginis Semen polysaccharides on intestinal microecology in rats with hyperuricemia

Yu Fu, Hongbin Qiu, Jing Zhao
article en
5 citations

Abstract

In summary, the present study substantiates the therapeutic potential of PSP in treating hyperuricemia through its dual action of lowering uric acid levels and imparting anti-inflammatory effects. The observed modulation of gut microbiota further supports the role of PSP in maintaining metabolic homeostasis. Future investigations should focus on the clinical applicability of PSP and elucidate the mechanisms underlying its beneficial impacts on hyperuricemia and associated metabolic disorders.

Frontiers in MicrobiologyVol. 16
Jiamusi University (CN), First Affiliated Hospital of Jiamusi University (CN)
Good health and well-being
Openalex Percentile: Top 3%
Gout, Hyperuricemia, Uric Acid
7.15
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