Effect and mechanism of Plantaginis Semen polysaccharides on intestinal microecology in rats with hyperuricemia
In summary, the present study substantiates the therapeutic potential of PSP in treating hyperuricemia through its dual action of lowering uric acid levels and imparting anti-inflammatory effects. The observed modulation of gut microbiota further supports the role of PSP in maintaining metabolic homeostasis. Future investigations should focus on the clinical applicability of PSP and elucidate the mechanisms underlying its beneficial impacts on hyperuricemia and associated metabolic disorders.
Authors
- Yu Fu (ORCID: https://orcid.org/0000-0002-1203-6970)
- Hongbin Qiu (ORCID: https://orcid.org/0000-0002-9547-6743)
- Jing Zhao (ORCID: https://orcid.org/0009-0006-1985-4809)
Institutions
- Jiamusi University (CN)
- First Affiliated Hospital of Jiamusi University (CN)
Publication Details
- Journal
- Frontiers in Microbiology
- Published
- 2025-03-26
- DOI
- https://doi.org/10.3389/fmicb.2025.1555734
- Citations
- 5
- Primary Topic
- Gout, Hyperuricemia, Uric Acid
- Type
- article
- Field-Weighted Citation Impact
- 7.15