Integrating machine learning and multi-omics analysis to reveal nucleotide metabolism-related immune genes and their functional validation in ischemic stroke
This study underscores the role of nucleotide metabolism in IS, identifying <i>CFL1, HMCES</i>, and <i>GIMAP1</i> as potential biomarkers and therapeutic targets, providing insights for IS diagnosis and therapy development.
Authors
- Tianzhi Li (ORCID: https://orcid.org/0000-0001-7787-0459)
- Sijie Zhang (ORCID: https://orcid.org/0000-0002-6167-8339)
- Jinsong Kang (ORCID: https://orcid.org/0000-0003-4875-1818)
- Jinshan He
- Chen Shao (ORCID: https://orcid.org/0000-0002-6899-5353)
- Yihan Wang (ORCID: https://orcid.org/0000-0002-5353-6250)
- Hongyan Li (ORCID: https://orcid.org/0000-0002-2191-1247)
- X. T. Kang
Institutions
- Jilin University (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-03-26
- DOI
- https://doi.org/10.3389/fimmu.2025.1561544
- Citations
- 1
- Primary Topic
- Neuroinflammation and Neurodegeneration Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.84