Comprehensive structural and functional analyses of RAD50 nsSNPs: from prediction to impact assessment
The study discloses the normative impact of RAD50 mutations on the pathophysiology of breast cancer. It can provide the basis to treat RAD50 mutation-deficient cells.
Authors
- Haleema Saadia (ORCID: https://orcid.org/0009-0008-4498-9005)
- Mirza Jawad ul Hasnain (ORCID: https://orcid.org/0000-0002-4949-8060)
- Arif Malik (ORCID: https://orcid.org/0000-0002-1894-6772)
- Ayesha Zahid (ORCID: https://orcid.org/0000-0003-3427-984X)
- Gul Zaib (ORCID: https://orcid.org/0009-0000-3859-8747)
- Samina Malik (ORCID: https://orcid.org/0009-0003-0652-8631)
Institutions
- University of Lahore (PK)
- East China Normal University (CN)
- Virtual University of Pakistan (PK)
Publication Details
- Journal
- Frontiers in Bioinformatics
- Published
- 2025-03-26
- DOI
- https://doi.org/10.3389/fbinf.2025.1535482
- Citations
- 1
- Primary Topic
- DNA Repair Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.81