The Role of circFAM53B in Regulating Choroidal Vascular Function in Pathological Myopia

Our results shed light on the involvement of the circFAM53B/miR-1248/THBS1 pathway in the decline of choroidal function observed in pathological myopia, expanding current understanding of the molecular mechanisms driving myopia development and offering potential therapeutic targets for choroid-related myopia.

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Publication Details

Journal
Current Eye Research
Published
2025-03-25
DOI
https://doi.org/10.1080/02713683.2025.2477550
Primary Topic
Circular RNAs in diseases
Type
article
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article

The Role of circFAM53B in Regulating Choroidal Vascular Function in Pathological Myopia

Boyong Zhang, Wenjing Wu, Fengju Zhang, Meng Guan et al.
Current Eye Research
Circular RNAs in diseases
article

The Role of circFAM53B in Regulating Choroidal Vascular Function in Pathological Myopia

Boyong Zhang, Wenjing Wu, Fengju Zhang, Meng Guan, Yu Li
article en

Abstract

Our results shed light on the involvement of the circFAM53B/miR-1248/THBS1 pathway in the decline of choroidal function observed in pathological myopia, expanding current understanding of the molecular mechanisms driving myopia development and offering potential therapeutic targets for choroid-related myopia.

Current Eye ResearchVol. 50(7)
Beijing Tongren Hospital (CN), Capital Medical University (CN), Kunming Medical University (CN), First Affiliated Hospital of Kunming Medical University (CN)
Openalex Percentile: Top 95%
Circular RNAs in diseases
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