Hyperorality in Frontotemporal Dementia: How Psychiatric and Neural Correlates Change During the Disease Course
Hyperorality emerged early in bvFTD and was accompanied by deficits in social cognition and complex-ritualistic behavior before clinically significant GMV loss. These findings suggest that early identification and management of hyperorality could improve neuropsychiatric trajectories in bvFTD.
Authors
- Irene Litvan (ORCID: https://orcid.org/0000-0002-3485-3445)
- Gwenn S. Smith (ORCID: https://orcid.org/0000-0003-0706-5440)
- Caroline Graff (ORCID: https://orcid.org/0000-0002-9949-2951)
- Adam M. Staffaroni (ORCID: https://orcid.org/0000-0002-3903-9805)
- Christopher B. Morrow (ORCID: https://orcid.org/0000-0003-4600-1802)
- Kyrana Tsapkini (ORCID: https://orcid.org/0000-0001-6020-5532)
- Zbigniew K. Wszołek (ORCID: https://orcid.org/0000-0001-5487-1053)
- Kimiko Domoto-Reilly
- Belén Pascual (ORCID: https://orcid.org/0000-0002-4467-7406)
- John Kornak (ORCID: https://orcid.org/0000-0002-0089-0619)
- Maria I. Lapid (ORCID: https://orcid.org/0000-0002-1163-5584)
- Katya Rascovsky
- R. Ryan Darby (ORCID: https://orcid.org/0000-0003-0326-1268)
- Alexander Pantelyat (ORCID: https://orcid.org/0000-0002-6427-7485)
- Chiadi U. Onyike (ORCID: https://orcid.org/0000-0003-2255-4437)
- Toji Miyagawa (ORCID: https://orcid.org/0000-0002-9387-0253)
- Andréia V. Faria (ORCID: https://orcid.org/0000-0002-1673-002X)
- Vidyulata Kamath (ORCID: https://orcid.org/0000-0001-7711-3597)
- Julio C. Rojas (ORCID: https://orcid.org/0000-0002-5730-5388)
- Mario F. Mendez (ORCID: https://orcid.org/0000-0001-6441-7989)
- Jeannie‐Marie Leoutsakos (ORCID: https://orcid.org/0000-0002-1010-1046)
- Nupur Ghoshal (ORCID: https://orcid.org/0000-0002-6680-6731)
- Akshata Balaji
Institutions
- Johns Hopkins University (US)
- Johns Hopkins Medicine (US)
Publication Details
- Journal
- Journal of Neuropsychiatry
- Published
- 2025-03-26
- DOI
- https://doi.org/10.1176/appi.neuropsych.20240134
- Citations
- 1
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 1.47