Evaluation of pituitary tumor volume as a prognostic factor in acromegaly: A cross-sectional study in two centers

PitNET volume was associated with the need for higher-line therapy to manage acromegaly but did not correlate with long-term disease control or with pre- or postsurgical IGF-1 levels. Nevertheless, a trend towards an inverse relationship between tumor volume and future disease control was observed. While macroadenoma classification remains crucial, among patients with macroadenomas, those with a volume exceeding 3697 mm³ could have worse prognosis.

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Publication Details

Journal
World Journal of Radiology
Published
2025-03-26
DOI
https://doi.org/10.4329/wjr.v17.i3.100168
Citations
3
Primary Topic
Pituitary Gland Disorders and Treatments
Type
article
Field-Weighted Citation Impact
3.88
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article

Evaluation of pituitary tumor volume as a prognostic factor in acromegaly: A cross-sectional study in two centers

Oswaldo Rincón, Angel Donato, Paulo Fernando de Arruda Mancera, Irisbel Guzman et al.
3 citations
World Journal of Radiology
Pituitary Gland Disorders and Treatments
3.88
article

Evaluation of pituitary tumor volume as a prognostic factor in acromegaly: A cross-sectional study in two centers

Oswaldo Rincón, Angel Donato, Paulo Fernando de Arruda Mancera, Irisbel Guzman, Juliana Rincon, Mauricio Álvarez, Natalia Lancheros
article en
3 citations

Abstract

PitNET volume was associated with the need for higher-line therapy to manage acromegaly but did not correlate with long-term disease control or with pre- or postsurgical IGF-1 levels. Nevertheless, a trend towards an inverse relationship between tumor volume and future disease control was observed. While macroadenoma classification remains crucial, among patients with macroadenomas, those with a volume exceeding 3697 mm³ could have worse prognosis.

World Journal of RadiologyVol. 17(3)
Military University Nueva Granada (CO), Hospital Militar Central (CO), Asociación Colombiana de Gastroenterología (CO), Fundación Universitaria Sanitas (CO)
Openalex Percentile: Top 7%
Pituitary Gland Disorders and Treatments
3.88
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