Desmoid-type fibromatosis in the puerperium: a case requiring pelvic exenteration

Desmoid-type fibromatosis (DF) is a rare, locally aggressive soft tissue tumor with no metastatic potential but a high recurrence rate. We present the case of a 28-year-old postpartum woman who developed a rapidly enlarging pelvic mass, which was later confirmed as DF via imaging and biopsy. The initial management with chemotherapy and radiotherapy was unsuccessful, necessitating radical surgical intervention with pelvic exenteration. Given its association with hormonal changes, particularly during pregnancy and the postpartum period, DF poses significant diagnostic and therapeutic challenges. This case underscores the importance of early recognition, multidisciplinary management, and individualized treatment strategies to optimize patient outcomes.