Accuracy and precision analyses of single-time-point dosimetry utilising physiologically-based pharmacokinetic modelling and non-linear mixed-effects modelling
STP dosimetry exhibits acceptable accuracy, although it shows a decrease in precision compared to ATP fitting. Precision information is clinically relevant for developing the optimal strategies for simplified dosimetry protocols.
Authors
- Supriyanto Ardjo Pawiro (ORCID: https://orcid.org/0000-0002-0028-1442)
- Ade Riana
- Indra Budiansah
- Ambros J. Beer (ORCID: https://orcid.org/0000-0001-9042-7806)
- Gerhard Glatting (ORCID: https://orcid.org/0000-0001-7916-1576)
- Deni Hardiansyah (ORCID: https://orcid.org/0000-0003-0984-8967)
Institutions
- Universität Ulm (DE)
- University of Indonesia (ID)
- Advanced Materials and Devices (United States) (US)
Publication Details
- Journal
- EJNMMI Physics
- Published
- 2025-03-26
- DOI
- https://doi.org/10.1186/s40658-025-00726-7
- Citations
- 4
- Primary Topic
- Radiopharmaceutical Chemistry and Applications
- Type
- article
- Field-Weighted Citation Impact
- 5.44
Funders
- Universität Ulm