Comparison of the pharmacokinetic variations of different concentrations of ropivacaine used for serratus anterior plane block in patients undergoing thoracoscopic lobectomy: a population pharmacokinetics analysis

This is the first population pharmacokinetic study of ropivacaine superficial serratus anterior plane block in patients undergoing thoracoscopic pulmonary resection. The model exhibits excellent stability and reliability, thereby offering valuable insights into personalized clinical drug administration. The concentration of ropivacaine and platelet count have significant impacts on the pharmacokinetic parameters of ropivacaine.