Trabecular texture and paraspinal muscle characteristics for prediction of first vertebral fracture: a QCT analysis from the AGES cohort
Trabecular texture and muscle parameters significantly improved prediction of first VF over age and BMI, but improvements were small compared to BMD, which remained the primary predictor for both sexes. Although muscle measures showed some predictive power, particularly in men, their clinical significance was marginal. Integral BMD should remain the focus for fracture risk assessment in clinical practice.
Authors
- Vilmundur Guðnason (ORCID: https://orcid.org/0000-0001-5696-0084)
- Sigurður Sigurdsson (ORCID: https://orcid.org/0000-0001-5439-3389)
- Stefan Bartenschlager (ORCID: https://orcid.org/0009-0001-4126-5975)
- Oliver Chaudry (ORCID: https://orcid.org/0000-0002-2179-3770)
- John D. Hummel (ORCID: https://orcid.org/0000-0002-2629-2553)
- Klaus Engelke (ORCID: https://orcid.org/0000-0001-9875-4123)
- Sandra Freitag-Wolf
- Claus‐C. Glüer
- Eren Yilmas
Institutions
- Friedrich-Alexander-Universität Erlangen-Nürnberg (DE)
- Christian-Albrechts-Universität zu Kiel (DE)
- Universitätsklinikum Erlangen (DE)
- Icelandic Heart Association (IS)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2025-03-26
- DOI
- https://doi.org/10.3389/fendo.2025.1566424
- Citations
- 1
- Primary Topic
- Bone health and osteoporosis research
- Type
- article
- Field-Weighted Citation Impact
- 1.72
Funders
- Friedrich-Alexander-Universität Erlangen-Nürnberg
- Bundesministerium für Bildung und Forschung