Effect of Marjoram Extract Containing Monoterpene Hydrocarbons, Oxygenated Monoterpene, and Phenolic Compounds on Some Gram-Positive and Gram-Negative Bacteria

In the present study, an attempt has been made to study the chemical composition and antimicrobial activity of water and methanol extracts of Origanum Majorana against four types of bacteria, two-gram negative (E. Coil, S. typhi) and two-gram positive (B.sub, s.aur) using agar well diffusion method. Flavonoids, tannins, anthraquinones, terpenes, coumarins, alkaloids, and saponins were the primary bioactive substances identified in Origanum majorana. The antibacterial activity revealed that the methanol extract of Origanum majorana only inhibited Bacillus subtilis and Staphylococcus aureus. However, some bacteria did not exhibit extract resistance. According to the current study, Origanum majorana extract may be a promising option for the hunt for a natural antibacterial agent. The scientific knowledge gained from this investigation will help determine the antibacterial values and explore additional pharmacological features