CRISPR/Cas9 mediated generation of zebrafish f9a mutant as a model for hemophilia B

This study created a zebrafish f9a knockout model that mimics the bleeding phenotype observed in hemophilia B patients, which will be valuable for evaluating novel therapeutic approaches for hemophilia B.

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Publication Details

Journal
Blood Coagulation & Fibrinolysis
Published
2025-03-19
DOI
https://doi.org/10.1097/mbc.0000000000001355
Primary Topic
CRISPR and Genetic Engineering
Type
article
Field-Weighted Citation Impact
0.00
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article

CRISPR/Cas9 mediated generation of zebrafish f9a mutant as a model for hemophilia B

Afnan Deebani, Sanchi Dhinoja, Anthony De Maria, Pudur Jagadeeswaran et al.
Blood Coagulation & Fibrinolysis
CRISPR and Genetic Engineering
article

CRISPR/Cas9 mediated generation of zebrafish f9a mutant as a model for hemophilia B

Afnan Deebani, Sanchi Dhinoja, Anthony De Maria, Pudur Jagadeeswaran, Ayah Al Qaryoute
article en

Abstract

This study created a zebrafish f9a knockout model that mimics the bleeding phenotype observed in hemophilia B patients, which will be valuable for evaluating novel therapeutic approaches for hemophilia B.

Blood Coagulation & FibrinolysisVol. 36(3)
University of North Texas (US)
Life below water
Openalex Percentile: Top 95%
CRISPR and Genetic Engineering
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CRISPR/Cas9 mediated generation of zebrafish f9a mutant as a model for hemophilia B — Afnan Deebani, Sanchi Dhinoja, et al. · Blood Coagulation & Fibrinolysis (2025) | TGRS Research Map | TGRS