CRISPR/Cas9 mediated generation of zebrafish f9a mutant as a model for hemophilia B
This study created a zebrafish f9a knockout model that mimics the bleeding phenotype observed in hemophilia B patients, which will be valuable for evaluating novel therapeutic approaches for hemophilia B.
Authors
- Afnan Deebani
- Sanchi Dhinoja
- Anthony De Maria
- Pudur Jagadeeswaran (ORCID: https://orcid.org/0000-0001-8892-4969)
- Ayah Al Qaryoute
Institutions
- University of North Texas (US)
Publication Details
- Journal
- Blood Coagulation & Fibrinolysis
- Published
- 2025-03-19
- DOI
- https://doi.org/10.1097/mbc.0000000000001355
- Primary Topic
- CRISPR and Genetic Engineering
- Type
- article
- Field-Weighted Citation Impact
- 0.00